Contrave prescription only diet pill – it is not available to buy over the counter, here is why

Contrave prescription only diet pill – it is not available to buy over the counter, here is why

Contrave in AustraliaContrave is a prescription-only diet pill produced in America by Orexigen. It contains just two active ingredients (bupropion HCl and naltrexone HCl), both of which are prescription medicines in their own right.

When used in conjunction with a low calorie diet and exercise, the use of Contrave for weight loss has been approved by the Food and Drug Administration (FDA), and although other countries have their own approval bodies, that fact that Contrave has been approved by the American FDA is a major point in its favour.

However, it must be remembered Contrave is a drug, not a supplement, and it has been designed specifically to help people who have a BMI of 27 kg/m2 or greater and are suffering from at least one medical problem that is weight-related.

Supplement manufacturers often make big promises for their products, but Orexigen is a biopharmaceutical company.

Their products are distributed via doctors, so there are no bold or exaggerated claims. Orexigen state their product may help some obese adults or overweight adults”, but their soft-sell approach still carries a lot of weight because Contrave has clinically-proven abilities.

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Contrave: What it is & What it Does

Orexigen don’t explain how the pills work, but one scholarly article suggests appetite suppression is probably the main benefit offered. Bupropion HCl has proven appetite suppressing capabilities, so this seems to be a highly plausible theory.

Two studies support the weight loss capabilities of a combination of bupropion HCl and naltrexone HCl. This may help explain why the FDA approved Contrave as a weight loss medication. Such approval does not come often. The last time a new weight loss medication was approved by the FDA was in 1999, when it approved the use of Orlistat.

One of the studies, conducted at the University of Pennsylvania School of Medicine (USA) was particularly supportive and, after 56 weeks of testing, the scientists concluded: The present findings support the efficacy of combined naltrexone/bupropion therapy as an adjunct to intensive BMOD for obesity.”

Key Ingredients – What Is In Contrave

  • Bupropion HCI: Often prescribed for the treatment of depression, bupropion HCI can stimulate certain areas of the brain and these abilities also appear to assist weight loss. In one study, conducted in America at the Duke University Medical Centre in Durham, volunteers who received the drug achieved an average weight loss of 12.9%.
  • Naltrexone HCI: A medication that is often prescribed to people who are being weaned off alcohol or opioid drugs. At least one study has been conducted into the abilities of naltrexone HCI as a weight loss aid, and the results were not supportive, but that is not to say it may not prove more useful when combined with other ingredients such as bupropion HCI.
How to Use Contrave – the formula has been approved to be used alongside dietary changes and regular exercise. New users are prescribed a lesser dose and must build up to the full dose of four pills a day.

For the first week one pill should be taken each morning. The following week a second pill must be taken on the evening. During week three, two pills are taken each morning, followed by one pill in the evening, and from week four onwards patients are required to take two pills each morning and two more every evening.

Side Effects & Health Considerations

A statement on the manufacturer’s website states Contrave can cause serious side effects, and puts particular emphasis on the possibility of users experiencing suicidal thoughts or actions.

Other Contrave-related side effects include:

  1. Swollen glands
  2. Eye problems
  3. Skin rashes and irritations
  4. Stomach problems
  5. Intestinal disorders
  6. Headaches
  7. Seizures
  8. Nausea
  9. Insomnia
  10. high blood pressure
  11. Changes to the heart rate
  12. Chest pains
  13. Manic episodes
  14. Liver damage
  15. Hepatitis

Testimonials & Feedback

Customer feedback indicates Contrave may work better for some users than others.[/plain]

“My doctors had me on Contrave for a few weeks now, but it doesn’t seem to be working for me. It appears to work for other people though so maybe it’s a metabolism thing.”

“It makes me feel very sick and dizzy, but I’ve lost a few pounds while taking Contrave. My doctor says the side effects may pass, but if they don’t I’m going to ask her to take me off Contrave and let me try something else.” 

“Contrave suppresses my appetite and helps me to eat less and it doesn’t give me any side effects. I’ve still got a long way to go, but I need to pull my belt a little tighter these days to avoid any unscheduled kneecap flashing.”

“I’ve lost 16lb in three weeks and have not experienced a single side effect.”


It is only possible to use Contrave if it is prescribed by a doctor.

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